- Preheat oven to 400 degrees. Prepare all ingredients. 
- Heat 3 tablespoons extra virgin olive oil in a skillet. Sauté shrimp until they just turn pink.  Add red pepper flakes.  (You will likely need to split this shrimp into two batches given the quantity.) Transfer sauteed shrimp to a baking dish. 
- Heat 3 tablespoons extra virgin olive oil in the same skillet.  Sauté chopped onions until cooked down, 3-4 minutes, then add chopped garlic and continue to sauté for another minute.  Add the dry white wine, and cook for 2 minutes over high heat. 
- Stir in the chopped tomatoes, fresh chopped parsley, Greek oregano, salt and fresh ground pepper to taste. Simmer, uncovered, for 15 minutes. 
- Pour the tomato mixture evenly over the shrimp in the baking dish. 
- Sprinkle crumbled feta cheese evenly over the tomato sauce. 
- Transfer the baking dish to a 400° oven and bake for 15 minutes or until feta cheese has melted and slightly browned on top.  Serve immediately over Penne pasta and some crusty bread.